Piazol -20mg

17.44% Govt. VAT/TAX will Be Added 

Presentation

Piazol 20 Capsule: Each capsule contains Omeprazole BP 20 mg as enteric coated pellets.

Description

Omeprazole is a proton pump inhibitor that suppresses the secretion of gastric acid by specific inhibition of the gastric proton pump (H+/K+ ATPase enzyme system) at the secretory surface of the gastric parietal cell. This effect on the final step of the gastric acid formation process is dose-dependent and provides for highly effective inhibition of both basal acid secretion and stimulated acid secretion, irrespective of the stimulus. Omeprazole is almost completely metabolized and rapidly eliminated mostly through urine.

Indications

Piazol is indicated in the treatment of:

• Peptic Ulcer Diseases (PUD).
• Reflux Esophagitis.
• NSAID associated gastric and duodenal ulcers or erosions.
• Helicobacter pylori eradication to reduce the risk of duodenal ulcer recurrence.
• Gastro-Esophageal Reflux Diseases (GERD).
• Acid related dyspepsia.
• Zollinger-Ellision syndrome.
• Erosive Esophagitis.
• Prevention of frequent heartburn.

Dosage & Administration

Gastric Ulcer: 20 mg once daily for 4-8 weeks.

Reflux Esophagitis: 20 mg once daily for 4-8 weeks.

Prevention of frequent heartburn: 20 mg orally once daily for 2 weeks.

NSAID associated gastric and duodenal ulcers or erosions: 20 mg once daily for 4-8 weeks.

Helicobacter pylori eradication to reduce the risk of duodenal ulcer recurrence:

Symptomatic Gastro-Esophageal Reflux Disease: 20 mg once daily for 4 weeks. Some patients may require 40 mg once daily. In event of recurrence, treatment may be repeated.

Acid related dyspepsia: 20 mg once daily for 4 weeks.

Healing of Erosive Esophagitis:   20 mg or 40 mg once daily for 4 to 8 Weeks.

Maintenance of Healing of Erosive Esophagitis: 20 mg once daily.

Risk Reduction of NSAID-Associated Gastric Ulcer: 20 mg or 40 mg once daily for up to 6 months.

Contraindications

Omeprazole is contraindicated in patients who have known hypersensitivity to Omeprazole or any component of the formulation.

Adverse Effects

Omeprazole is generally well tolerated. Nausea, diarrhea, flatulence, abdominal pain, constipation, dizziness and headache have been stated to be generally mild and transient and not requiring a reduction in dosage.

Precautions

Omeprazole may alleviate symptoms and delay diagnosis of gastric carcinoma.

Pregnancy & Lactation

Recent studies show no adverse effects of Omeprazole on pregnancy or on the health of the fetus or newborn child. Omeprazole can be used during pregnancy.

Omeprazole is excreted in breast milk, but it is not likely to influence the child when therapeutic doses are used.

Drug interactions

Omeprazole interacts with following drugs:

• Diazepam
• Warfarin
• Phenytoin

There is no evidence of an interaction of Omeprazole with theophylline, propranolol and antacids.

Storage

Store in a cool & dry place. Keep away from light. Keep out of reach of children.

Packaging

Piazol 20 Capsule: Each box contains 100 capsules in Alu-Alu blister pack.